triggerstrategy

Trigger Strategy in Clinical Trials

CRAN Package

The trigger strategy is a general framework for a multistage statistical design with multiple hypotheses, allowing an adaptive selection of interim analyses. The selection of interim stages can be associated with some prespecified endpoints which serve as the trigger. This selection allows us to refine the critical boundaries in hypotheses testing procedures, and potentially increase the statistical power. This package includes several trial designs using the trigger strategy. See Gou, J. (2023), "Trigger strategy in repeated tests on multiple hypotheses", Statistics in Biopharmaceutical Research, 15(1), 133-140, and Gou, J. (2022), "Sample size optimization and initial allocation of the significance levels in group sequential trials with multiple endpoints", Biometrical Journal, 64(2), 301-311.

  • Version1.2.0
  • R versionunknown
  • LicenseGPL-3
  • Needs compilation?No
  • Last release07/04/2023

Team


Insights

Last 30 days

This package has been downloaded 120 times in the last 30 days. Now we're getting somewhere! Enough downloads to populate a lively group chat. The following heatmap shows the distribution of downloads per day. Yesterday, it was downloaded 2 times.

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0 downloadsFeb 9, 2025
0 downloadsFeb 10, 2025
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11 downloadsFeb 12, 2025
4 downloadsFeb 13, 2025
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2 downloadsFeb 15, 2025
3 downloadsFeb 16, 2025
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5 downloadsFeb 19, 2025
14 downloadsFeb 20, 2025
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1 downloadsFeb 22, 2025
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2 downloadsFeb 28, 2025
2 downloadsMar 1, 2025
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3 downloadsMar 12, 2025
2 downloadsMar 13, 2025
0 downloadsMar 14, 2025
0 downloadsMar 15, 2025
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The following line graph shows the downloads per day. You can hover over the graph to see the exact number of downloads per day.

Last 365 days

This package has been downloaded 1,590 times in the last 365 days. Now we’re talking! This work is officially 'heard of in academic circles', just like those wild research papers on synthetic bananas. The day with the most downloads was Sep 11, 2024 with 19 downloads.

The following line graph shows the downloads per day. You can hover over the graph to see the exact number of downloads per day.

Data provided by CRAN


Binaries


Dependencies

  • Imports4 packages