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Evaluation of Genotyping Error in Genotype-by-Sequencing Data
This is a small, lightweight package that lets users investigate the distribution of genotypes in genotype-by-sequencing (GBS) data where they expect (by and large) Hardy-Weinberg equilibrium, in order to assess rates of genotyping errors and the dependence of those rates on read depth. It implements a Markov chain Monte Carlo (MCMC) sampler using 'Rcpp' to compute a Bayesian estimate of what we call the heterozygote miscall rate for restriction-associated digest (RAD) sequencing data and other types of reduced representation GBS data. It also provides functions to generate plots of expected and observed genotype frequencies. Some background on these topics can be found in a recent paper "Recent advances in conservation and population genomics data analysis" by Hendricks et al. (2018)
- Version0.0.2
- R version≥ 3.3.0
- LicenseCC0
- Needs compilation?Yes
- Last release08/11/2021
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Team
Eric C. Anderson
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- Depends1 package
- Imports8 packages
- Suggests2 packages
- Linking To1 package