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Genetic Association Models for X-Chromosome SNPS on Continuous, Binary and Survival Outcomes
The expression of X-chromosome undergoes three possible biological processes: X-chromosome inactivation (XCI), escape of the X-chromosome inactivation (XCI-E),and skewed X-chromosome inactivation (XCI-S). To analyze the X-linked genetic association for phenotype such as continuous, binary, and time-to-event outcomes with the actual process unknown, we propose a unified approach of maximizing the likelihood or partial likelihood over all of the potential biological processes. The methods are described in Wei Xu, Meiling Hao (2017) doi:10.1002/gepi.22097. And also see Dongxiao Han, Meiling Hao, Lianqiang Qu, Wei Xu (2019) doi:10.1177/0962280219859037.
- Version1.0.1
- R versionunknown
- LicenseGPL-2
- Needs compilation?No
- Wei Xu, Meiling Hao (2017) doi:10.1002/gepi.22097
- Dongxiao Han, Meiling Hao, Lianqiang Qu, Wei Xu (2019) doi:10.1177/0962280219859037
- Last release08/20/2019
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Team
Yi Zhu
Wei Xu
Show author detailsRolesAuthorMeiling Hao
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